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Amphotericin B

" in MedChemExpress (MCE) Product Catalog:

10

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Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0221
    Amphotericin B
    Maximum Cited Publications
    13 Publications Verification

    		 Fungal Antibiotic Bacterial Parasite Infection Cancer
    Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
    <em>Amphotericin</em> <em>B</em>
  • HY-135327
    Amphotericin B methyl ester

    		HIV Fungal Infection
    Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication .
    <em>Amphotericin</em> <em>B</em> methyl ester
  • HY-135327A
    Amphotericin B methyl ester hydrochloride

    		HIV Fungal Infection
    Amphotericin B methyl ester hydrochloride is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester hydrochloride is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester hydrochloride disrupts HIV-1 particle production and potently inhibits HIV-1 replication .
    <em>Amphotericin</em> <em>B</em> methyl ester hydrochloride
  • HY-B0221R
    Amphotericin B (Standard)

    		Fungal Antibiotic Bacterial Parasite Infection Cancer
    Amphotericin B (Standard) is the analytical standard of Amphotericin B. This product is intended for research and analytical applications. Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
    <em>Amphotericin</em> <em>B</em> (Standard)
  • HY-B0221A
    Amphotericin B trihydrate

    		Antibiotic Fungal Bacterial Parasite Infection Inflammation/Immunology Cancer
    Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures of Streptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity .
    <em>Amphotericin</em> <em>B</em> trihydrate
  • HY-B0221S
    Amphotericin B-13C6

    		Isotope-Labeled Compounds Cancer
    Amphotericin B- 13C6 is 13C labeled Amphotericin B (HY-B0221). Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
    <em>Amphotericin</em> <em>B</em>-13C6
  • HY-114664
    KNK423

    		HSP Infection Cancer
    KNK423 is a specific heat shock protein (HSP) synthesis inhibitor. KNK423 improves the efficiency of Amphotericin B in inhibiting resistant Aspergillus terreus by blocking HSP70. KNK423 can be used in cancer and bacterial infection research .
    KNK423
  • HY-136153
    Amphotericin X1

    		Fungal Infection
    Amphotericin X1 is an 13-O-methyl derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, C.parapsilosis 937A, Cryptococcus neoformans 451, Aspergillus niger 57A and A.fumigatus with MIC values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL and 2 μg/mL, respectively .
    <em>Amphotericin</em> X1
  • HY-161091
    AM-2-19

    		Fungal Infection
    AM-2-19 (SF001) is an ergosterol-extracting polyene antifungal that is discovered through modifications to the amphotericin B toxin by chemists .
    AM-2-19
  • HY-137500
    NT1-014B

    		Liposome Neurological Disease
    NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection .
    NT1-014B

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